Dr’in Susanne Reger-Tan

Clinician Scientist. Ärztin.

Klinik für Endokrinologie, Diabetologie und Stoffwechsel. Universitätsmedizin Essen

• Digitales Diabetesmanagement
• Onco-Diabetes
• Polyzystisches Ovarsyndrom

• www.webofscience.com/wos/author/record/31753636
• Van Baal L, Reinold J, Benson S, Diehl A, Witzke O, Fuhrer D, Tan S. Implications of a HbA1c based diabetes screening on prevalence and impact of dysglycemia in patients with COVID-19. J Clin Endocrinol Metab. 2022 Oct 12;. doi: 10.1210/clinem/dgac590. [Epub ahead of print] PubMed PMID: 36221157.
• Antel J, Tan S, Grabler M, Ludwig C, Lohkemper D, Brandenburg T, Barth N, Hinney A, Libuda L, Remy M, Milos G, Hebebrand J. Rapid amelioration of anorexia nervosa in a male adolescent during metreleptin treatment including recovery from hypogonadotropic hypogonadism. Eur Child Adolesc Psychiatry. 2022 Oct;31(10):1573-1579. doi: 10.1007/s00787-021-01778-7. Epub 2021 May 9. PMID: 33966118; PMCID: PMC8106547.
• Kempf K, Röhling M, Banzer W, Braumann KM, Halle M, Schaller N, McCarthy D, Predel HG, Schenkenberger I, Tan S, Toplak H, Martin S, Berg A, On Behalf Of The Acoorh Study Group. High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome-A Subanalysis of the Randomised-Controlled ACOORH Trial. Nutrients. 2022 Jul 30;14(15). doi: 10.3390/nu14153161. PMID: 35956337; PMCID: PMC9370463.
• Kempf K, Röhling M, Banzer W, Braumann KM, Halle M, Schaller N, McCarthy D, Predel HG, Schenkenberger I, Tan S, Toplak H, Martin S, Berg A, Acoorh Study Group. Early and Strong Leptin Reduction Is Predictive for Long-Term Weight Loss during High-Protein, Low-Glycaemic Meal Replacement-A Subanalysis of the Randomised-Controlled ACOORH Trial. Nutrients. 2022 Jun 18;14(12). doi: 10.3390/nu14122537. PMID: 35745267; PMCID: PMC9229506.
• Moradian S, Teufel M, Jahre L, Musche V, Fink M, Dinse H, Schweda A, Weismüller B, Dörrie N, Tan S, Skoda EM, Bäuerle A. Mental health burden of patients with diabetes before and after the initial outbreak of COVID-19: predictors of mental health impairment. BMC Public Health. 2021 Nov 11;21(1):2068. doi: 10.1186/s12889-021-12101-z. PMID: 34763688; PMCID: PMC8582238.
• Tan S, Ignatenko S, Wagner F, Dokras A, Seufert J, Zwanziger D, Dunschen K, Zakaria M, Huseinovic N, Basson CT, Mahling P, Fuhrer D, Hinder M. Licogliflozin versus placebo in women with polycystic ovary syndrome: A randomized, double-blind, phase 2 trial. Diabetes Obes Metab. 2021 Nov;23(11):2595-2599. doi: 10.1111/dom.14495. Epub 2021 Jul 27. PMID: 34263971.
• Reinhardt W, Mülling N, Behrendt S, Benson S, Dolff S, Führer D, Tan S. Association between albuminuria and thyroid function in patients with chronic kidney disease. Endocrine. 2021 Aug;73(2):367-373. doi: 10.1007/s12020-021-02640-1. Epub 2021 Feb 11. PMID: 33575899; PMCID: PMC8263419.
• Kempf K, Röhling M, Banzer W, Braumann KM, Halle M, McCarthy D, Predel HG, Schenkenberger I, Tan S, Toplak H, Berg A, Martin S, On Behalf Of Acoorh Study Group. High-Protein, Low-Glycaemic Meal Replacement Decreases Fasting Insulin and Inflammation Markers-A 12-Month Subanalysis of the ACOORH Trial. Nutrients. 2021 Apr 23;13(5). doi: 10.3390/nu13051433. PMID: 33922802; PMCID: PMC8145939.
• Musche V, Kohler H, Bäuerle A, Schweda A, Weismüller B, Fink M, Schadendorf T, Robitzsch A, Dörrie N, Tan S, Teufel M, Skoda EM. COVID-19-Related Fear, Risk Perception, and Safety Behavior in Individuals with Diabetes. Healthcare (Basel). 2021 Apr 18;9(4). doi: 10.3390/healthcare9040480. PMID: 33919519; PMCID: PMC8072870.
• Halle M, Röhling M, Banzer W, Braumann KM, Kempf K, McCarthy D, Schaller N, Predel HG, Scholze J, Führer-Sakel D, Toplak H, Berg A. Meal replacement by formula diet reduces weight more than a lifestyle intervention alone in patients with overweight or obesity and accompanied cardiovascular risk factors-the ACOORH trial. Eur J Clin Nutr. 2021 Apr;75(4):661-669. doi: 10.1038/s41430-020-00783-4. Epub 2020 Oct 30. PMID: 33128036.
• Hebebrand J, Antel J, Tan S, Wabitsch M, Wiesing U, Barth N, Ludwig C, Bühlmeier J, Libuda L, Milos G, Hinney A. Kurzzeitige Behandlung von Patient_innen mit Anorexia nervosa mit rekombinant hergestelltem Human-Leptin (Metreleptin): Rasch einsetzende positive Effekte auf Stimmung, Kognition und Verhalten. Z Kinder Jugendpsychiatr Psychother. 2021 Jan;49(1):1-5. doi: 10.1024/1422-4917/a000775. PMID: 33423560.
• Milos G, Antel J, Kaufmann LK, Barth N, Koller A, Tan S, Wiesing U, Hinney A, Libuda L, Wabitsch M, von Känel R, Hebebrand J. Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects. Transl Psychiatry. 2020 Aug 27;10(1):303. doi: 10.1038/s41398-020-00977-1. PMID: 32855384; PMCID: PMC7453199.
• Röhling M, Kempf K, Banzer W, Berg A, Braumann KM, Tan S, Halle M, McCarthy D, Pinget M, Predel HG, Scholze J, Toplak H, Martin S, Acoorh Study Group. Prediabetes Conversion to Normoglycemia Is Superior Adding a Low-Carbohydrate and Energy Deficit Formula Diet to Lifestyle Intervention-A 12-Month Subanalysis of the ACOORH Trial. Nutrients. 2020 Jul 7;12(7). doi: 10.3390/nu12072022. PMID: 32646010; PMCID: PMC7400892.
• Thiel J, Alter C, Luppus S, Eckstein A, Tan S, Führer D, Pastille E, Westendorf AM, Buer J, Hansen W. MicroRNA-183 and microRNA-96 are associated with autoimmune responses by regulating T cell activation. J Autoimmun. 2019 Jan;96:94-103. doi: 10.1016/j.jaut.2018.08.010. Epub 2018 Sep 7. PMID: 30201436.
• Reinhardt W, Kübber H, Dolff S, Benson S, Führer D, Tan S. Rapid recovery of hypogonadism in male patients with end stage renal disease after renal transplantation. Endocrine. 2018 Apr;60(1):159-166. doi: 10.1007/s12020-018-1543-2. Epub 2018 Feb 1. PMID: 29392618.
• Anastasiou OE, Canbay A, Fuhrer D, Reger-Tan S. Metabolic and androgen profile in underweight women with polycystic ovary syndrome. Arch Gynecol Obstet. 2017 Aug;296(2):363-371. doi: 10.1007/s00404-017-4422-9. Epub 2017 Jun 12. PMID: 28608050.
• Tan S, Vollmar N, Benson S, Sowa JP, Bechmann LP, Gerken G, Fuhrer D, Canbay A. Liver Injury Indicating Fatty Liver but Not Serologic NASH Marker Improves under Metformin Treatment in Polycystic Ovary Syndrome. Int J Endocrinol. 2015;2015:254169. doi: 10.1155/2015/254169. Epub 2015 Mar 19. PMID: 25873949; PMCID: PMC4383456.
• Tan S, Dieterle S, Pechlavanis S, Janssen OE, Fuhrer D. Thyroid autoantibodies per se do not impair intracytoplasmic sperm injection outcome in euthyroid healthy women. Eur J Endocrinol. 2014 Apr;170(4):495-500. doi: 10.1530/EJE-13-0790. Print 2014 Apr. PMID: 24394727.
• Wojciechowski P, Lipowska A, Rys P, Ewens KG, Franks S, Tan S, Lerchbaum E, Vcelak J, Attaoua R, Straczkowski M, Azziz R, Barber TM, Hinney A, Obermayer-Pietsch B, Lukasova P, Bendlova B, Grigorescu F, Kowalska I, Goodarzi MO, Strauss JF 3rd, McCarthy MI, Malecki MT. Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome: a systematic review and meta-analysis. Diabetologia. 2012 Oct;55(10):2636-2645. doi: 10.1007/s00125-012-2638-6. Epub 2012 Jul 18. Review. PMID: 22801903; PMCID: PMC3433670.
• Klenke S, Tan S, Hahn S, Mann K, Hauner H, Manthey I, Peters J, Siffert W, Frey UH. A functional GNAQ promoter haplotype is associated with altered Gq expression and with insulin resistance and obesity in women with polycystic ovary syndrome. Pharmacogenet Genomics. 2010 Aug;20(8):476-84. doi: 10.1097/FPC.0b013e32833b7497. PMID: 20562673.
• Tan S, Scherag A, Janssen OE, Hahn S, Lahner H, Dietz T, Scherag S, Grallert H, Vogel CI, Kimmig R, Illig T, Mann K, Hebebrand J, Hinney A. Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS). BMC Med Genet. 2010 Jan 21;11:12. doi: 10.1186/1471-2350-11-12. PMID: 20092643; PMCID: PMC2824654.
• Benson S, Hahn S, Tan S, Janssen OE, Schedlowski M, Elsenbruch S. Maladaptive coping with illness in women with polycystic ovary syndrome. J Obstet Gynecol Neonatal Nurs. 2010 Jan-Feb;39(1):37-45. doi: 10.1111/j.1552-6909.2009.01086.x. PMID: 20409101.
• Tan S, Bechmann LP, Benson S, Dietz T, Eichner S, Hahn S, Janssen OE, Lahner H, Gerken G, Mann K, Canbay A. Apoptotic markers indicate nonalcoholic steatohepatitis in polycystic ovary syndrome. J Clin Endocrinol Metab. 2010 Jan;95(1):343-8. doi: 10.1210/jc.2009-1834. Epub 2009 Nov 11. PMID: 19906783.
• Benson S, Arck PC, Tan S, Hahn S, Mann K, Rifaie N, Janssen OE, Schedlowski M, Elsenbruch S. Disturbed stress responses in women with polycystic ovary syndrome. Psychoneuroendocrinology. 2009 Jun;34(5):727-35. doi: 10.1016/j.psyneuen.2008.12.001. Epub 2009 Jan 15. PMID: 19150179.
• Benson S, Hahn S, Tan S, Mann K, Janssen OE, Schedlowski M, Elsenbruch S. Prevalence and implications of anxiety in polycystic ovary syndrome: results of an internet-based survey in Germany. Hum Reprod. 2009 Jun;24(6):1446-51. doi: 10.1093/humrep/dep031. Epub 2009 Feb 16. PMID: 19223290.
• Benson S, Arck PC, Tan S, Mann K, Hahn S, Janssen OE, Schedlowski M, Elsenbruch S. Effects of obesity on neuroendocrine, cardiovascular, and immune cell responses to acute psychosocial stress in premenopausal women. Psychoneuroendocrinology. 2009 Feb;34(2):181-189. doi: 10.1016/j.psyneuen.2008.08.019. Epub 2008 Oct 5. PMID: 18838227.
• Tan S, Hahn S, Benson S, Janssen OE, Dietz T, Kimmig R, Hesse-Hussain J, Mann K, Schedlowski M, Arck PC, Elsenbruch S. Psychological implications of infertility in women with polycystic ovary syndrome. Hum Reprod. 2008 Sep;23(9):2064-71. doi: 10.1093/humrep/den227. Epub 2008 Jun 25. PMID: 18583330.
• Benson S, Janssen OE, Hahn S, Tan S, Dietz T, Mann K, Pleger K, Schedlowski M, Arck PC, Elsenbruch S. Obesity, depression, and chronic low-grade inflammation in women with polycystic ovary syndrome. Brain Behav Immun. 2008 Feb;22(2):177-84. doi: 10.1016/j.bbi.2007.07.003. Epub 2007 Aug 22. PMID: 17716857.
• Tan S, Hahn S, Janssen OE. [The polycystic ovary syndrome--metabolic consequences]. Gynakol Geburtshilfliche Rundsch. 2008;48(1):16-23. doi: 10.1159/000111466. Epub 2008 Jan 17. Review. PMID: 18209495.
• Janssen OE, Hahn S, Tan S, Benson S, Elsenbruch S. Mood and sexual function in polycystic ovary syndrome. Semin Reprod Med. 2008 Jan;26(1):45-52. doi: 10.1055/s-2007-992924. Review. PMID: 18181082.
• Tan S, Hahn S, Benson S, Dietz T, Lahner H, Moeller LC, Schmidt M, Elsenbruch S, Kimmig R, Mann K, Janssen OE. Metformin improves polycystic ovary syndrome symptoms irrespective of pre-treatment insulin resistance. Eur J Endocrinol. 2007 Nov;157(5):669-76. doi: 10.1530/EJE-07-0294. PMID: 17984248.
• Hahn S, Backhaus M, Broecker-Preuss M, Tan S, Dietz T, Kimmig R, Schmidt M, Mann K, Janssen OE. Retinol-binding protein 4 levels are elevated in polycystic ovary syndrome women with obesity and impaired glucose metabolism. Eur J Endocrinol. 2007 Aug;157(2):201-7. doi: 10.1530/EJE-07-0143. PMID: 17656599.
• Hahn S, Tan S, Sack S, Kimmig R, Quadbeck B, Mann K, Janssen OE. Prevalence of the metabolic syndrome in German women with polycystic ovary syndrome. Exp Clin Endocrinol Diabetes. 2007 Feb;115(2):130-5. doi: 10.1055/s-2007-967093. PMID: 17318774.
• Hahn S, Kuehnel W, Tan S, Kramer K, Schmidt M, Roesler S, Kimmig R, Mann K, Janssen OE. Diagnostic value of calculated testosterone indices in the assessment of polycystic ovary syndrome. Clin Chem Lab Med. 2007;45(2):202-7. doi: 10.1515/CCLM.2007.031. PMID: 17311509.
• Hahn S, Frey UH, Siffert W, Tan S, Mann K, Janssen OE. The CC genotype of the GNAS T393C polymorphism is associated with obesity and insulin resistance in women with polycystic ovary syndrome. Eur J Endocrinol. 2006 Nov;155(5):763-70. doi: 10.1530/eje.1.02275. PMID: 17062894.
• Hahn S, Haselhorst U, Tan S, Quadbeck B, Schmidt M, Roesler S, Kimmig R, Mann K, Janssen OE. Low serum 25-hydroxyvitamin D concentrations are associated with insulin resistance and obesity in women with polycystic ovary syndrome. Exp Clin Endocrinol Diabetes. 2006 Nov;114(10):577-83. doi: 10.1055/s-2006-948308. PMID: 17177140.
• Hahn S, Benson S, Elsenbruch S, Pleger K, Tan S, Mann K, Schedlowski M, van Halteren WB, Kimmig R, Janssen OE. Metformin treatment of polycystic ovary syndrome improves health-related quality-of-life, emotional distress and sexuality. Hum Reprod. 2006 Jul;21(7):1925-34. doi: 10.1093/humrep/del069. Epub 2006 Mar 20. PMID: 16549423.
• Hahn S, Bering van Halteren W, Roesler S, Schmidt M, Kimmig R, Tan S, Mann K, Janssen OE. The combination of increased ovarian volume and follicle number is associated with more severe hyperandrogenism in German women with polycystic ovary syndrome. Exp Clin Endocrinol Diabetes. 2006 Apr;114(4):175-81. doi: 10.1055/s-2006-924063. PMID: 16705549.
• Elsenbruch S, Benson S, Hahn S, Tan S, Mann K, Pleger K, Kimmig R, Janssen OE. Determinants of emotional distress in women with polycystic ovary syndrome. Hum Reprod. 2006 Apr;21(4):1092-9. doi: 10.1093/humrep/dei409. Epub 2006 Feb 3. PMID: 16459352.
• Hahn S, Haselhorst U, Quadbeck B, Tan S, Kimmig R, Mann K, Janssen OE. Decreased soluble leptin receptor levels in women with polycystic ovary syndrome. Eur J Endocrinol. 2006 Feb;154(2):287-94. doi: 10.1530/eje.1.02078. PMID: 16452543.
• Hahn S, Janssen OE, Tan S, Pleger K, Mann K, Schedlowski M, Kimmig R, Benson S, Balamitsa E, Elsenbruch S. Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome. Eur J Endocrinol. 2005 Dec;153(6):853-60. doi: 10.1530/eje.1.02024. PMID: 16322391.
• Hahn S, Tan S, Elsenbruch S, Quadbeck B, Herrmann BL, Mann K, Janssen OE. Clinical and biochemical characterization of women with polycystic ovary syndrome in North Rhine-Westphalia. Horm Metab Res. 2005 Jul;37(7):438-44. doi: 10.1055/s-2005-870236. PMID: 16034717.
• Hahn S, Fingerhut A, Khomtsiv U, Khomtsiv L, Tan S, Quadbeck B, Herrmann BL, Knebel B, Müller-Wieland D, Mann K, Janssen OE. The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is associated with a lower hirsutism score and increased insulin sensitivity in women with polycystic ovary syndrome. Clin Endocrinol (Oxf). 2005 May;62(5):573-9. doi: 10.1111/j.1365-2265.2005.02261.x. PMID: 15853827.

• SmartDiabetesCare

• Bytes4Diabetes 2022 (1. Preis)
• Focus Top Nationale Klinik Diabetes 2023
• Focus Top Mediziner Diabetologie (seit 2021)
• Focus Top Mediziner Endokrinologie (seit 2022)
• Lehrpreis „Beste evaluierte Lehrveranstaltung“ für das „Seminar Differentialdiagnostik Innere Medizin" 2016-2018 (Medizinische Fakultät, Universität Duisburg-Essen)
• Posterpreis der Endocrine Society Trainee Poster Competition 2008
• 1. Nachwuchsförderpreis der Sektion Angewandte Endokrinologie, Deutsche Gesellschaft für Endokrinologie 2007
• Posterpreis der Rheinisch-Westfälischen Gesellschaft für Innere Medizin 2004

• Leitlinien-Koordinatorin AWMF-Leitlinie PCOS

• www.endokrinologie.de/

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orcid.org/0000-0003-2692-8643

2010 Fachärztin für Innere Medizin, Endokrinologie
und Diabetologie
2018 Diabetologin DDG
2019 Wundexpertin ICW
2021 Zusatzbezeichnung Ernährungsmedizin

1997 Studium der Humanmedizin
2004 Approbation
2007 Promotion
2015 Habilitation für das Fach Innere Medizin

2004 Assistenzärztin
2015 Oberärztin. Leitungsteam der Klinik.
Leiterin des Diabeteszentrums.
2018 Mitglied Lenkungsgremium des Wundzentrums
2021 Leitlinien-Koordinatorin AWMF-Leitlinie PCOS
2021 Mitglied Lenkungsgruppe SmartHospital